Figure 1.
Golgi compartments and function. Some proteins are transported to the cell surface after synthesis at the endoplasmic reticulum (ER), sorting, and processing in the Golgi complex. The trans-Golgi network (TGN) and cis-Golgi network (CGN) are responsible for protein sorting via vesicle transport from ER to CGN and also in retrograde direction. In contrast, granins are sorted though the TGN and stored in secretory granules. Some granins are known to be proteolytically processed and secreted to extracellular space.
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