Table 2. Pharmacokinetics of non-glycosylated and glycosylated rhGM-CSF in rats after a single iv injection.


 

t1/2 α
(min)

t1/2 β
(min)

CL
(mL/min)

non-glycosylated rhGM-CSF

2.1 ± 0.2

5 ± 10

2.83 ± 0.09

glycosylated rhGM-CSF

4.9 ± 0.6

3 ± 10

1.07 ± 0.05


Supported by UNESCO / MIRCEN network