Table 5. The substrate-concentration independent enantiomeric ratio for the various batches, revealing evidence of the effect of methyl branching and confirming the effect of water activity on the esterification reactions. The value of the equilibrium constant, K, is found in parentheses after the enantiomeric ratio if K was not zero.

Ibuprofen Concentration

Enatiomeric Ratio

 Isooctane

 a_w = 0.73 

14.9 ± 2.7

a_w = 0.59

9.7 ± 1.9

a_w = 0.43

4.0 ± 0.8

 2,5-Dimethylhexane 

a_w = 0.73

11.0 ± 1.6

a_w = 0.59

6.5 ± 1.4

a_w = 0.43

NR

 2-Methylheptane

a_w = 0.73

10.1 ± 1.4

a_w = 0.59

6.1 ± 1.3

a_w = 0.43

NR

 n-Octane

a_w = 0.73

6.6 ± 1.1

a_w = 0.59

3.4 ± 0.3

a_w = 0.43

2.0 ± 0.4
(7.3 ± 1.3)