Table 1. Mean percentage of inhibition of protease activity from extracts of recombinant H. contortus Cysteine Protease.


Inhibitorb

Substratesa

 

YVAD

FR

RR

 E-64

98

100

100

 EDTA

33

45

22

 Pepstatin

0.0

0.0

2.1

 PMSFc

0.0

2.3

14.4

aPeptide substrates FR-AMC, RR-AMC, and YVAD-AMC.
bMeans percentage of inhibition (n = 5), compared to non-inhibited controls.
cPhenylmethylsulfonyl fluoride.


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