Table 3. Structure-Activity Relationships models: statistics.

 Characteristic (abbreviation)

SAR model

Eq(1)

Eq(2)

 Correlation coefficient (r)

0.9472

0.9868

 Squared correlation coefficient (r²)

0.8972

0.9737

 Adjusted squared correlation coefficient (r²_adj)

0.8896

0.9695

 Standard error of estimated (s_est)

0.2355

0.1238

 Fisher parameter of estimated (F_est)

118

231

 Type I error associated with the Fisher parameter of estimated (p_est)

4.56·10^-14

1.50·10^-21

 Leave-one-out cross-validation score (r²_loo-cv)

0.8745

0.9650

 Fisher parameter of predicted (F_pred)

93

172

 Fisher probability of predicted (p_pred)

7.58·10^-13

9.34 10^-20

 Standard error of predict (s_loo)

0.2613

0.1429

 Difference between squared correlation coefficient and leave-one-out cross-
 validation score (r² - r²_loo-cv)

0.0227

0.0086