Figure 4. Area of silicone elastomer covered by S. epidermidis biofilm at various time intervals. Values are the mean of measures obtained from 15 photographs of each of 3 discs. Error bars are the standard error of the mean (n = 3). Asterisks indicate that the area covered by biofilm was significantly different (ANOVA, p < 0.05) than that found on smooth surfaces (controls, pattern 0).