Figure 4.
Average displacements of the substrate and inhibitor compared
with position of substrate in wild-type enzyme.
C128D-N, arginine in Asp
128Asn
mutant;
C141H-F, arginine His 141Phe
mutant;
C141H-N, arginine in His 141Asn
mutant;
C141H-F*, lysine in His 141Phe
mutant;
C141H-N*, lysine in His 141Asn
mutant;
C141*, lysine in wild type enzyme.