Process Biotechnology
Electronic Journal of Biotechnology ISSN: 0717-3458 Vol. 6 No. 2, Issue of August 15, 2003
© 2003 by Pontificia Universidad Católica de Valparaíso -- Chile Received December 23, 2002 / Accepted July 15, 2003
SHORT COMMUNICATION


Infection of Caenorhabditis elegans by Salmonella typhi Ty2

Javier Santander
Laboratorio de Bacteriología
Instituto de Biología
Pontificia Universidad Católica de Valparaíso
Av. Brasil 2950, Valparaíso, Chile
Tel: 56 32 273118
Fax 56 32 273109
E-mail: jrobeson@ucv.cl

Juan Carlos Espinoza
Laboratorio de Bioquímica y Virología
Instituto de Ciencias Biológicas y Químicas
Universidad de Valparaíso
Valparaíso, Chile
Avenida Gran Bretaña 1111
P.O.Box 5030
Valparaíso, Chile
Tel: 56 32 508072
Fax: 56 32 508072
E-mail: juan.espinoza@uv.cl 

María Soledad Campano
Laboratorio de Nematología
Instituto de Biología
Pontificia Universidad Católica de Valparaíso
Av. Brasil 2950 Valparaíso, Chile
Tel: 56 32 273118
Fax 56 32 273109
E-mail: jrobeson@ucv.cl 

James Robeson*
Laboratorio de Bacteriología
Instituto de Biología
Pontificia Universidad Católica de Valparaíso
Av. Brasil 2950 Valparaíso, Chile
Tel: 56 32 273118
Fax 56 32 273109
E-mail: jrobeson@ucv.cl

* Corresponding author

Financial support: Vice-Rectoria de Investigación y Estudios Avanzados, Universidad Católica de Valparaíso. Proyecto D.I.UCV 122.770.2002.

Keywords: Caenorhabditis elegans, invasiveness, Salmonella typhi Ty2.

Abstract
Full Text

Several serovars of Salmonella infect and kill the nematode C. elegans. However, here we report that Salmonella typhi Ty2, a representative strain of this human pathogen, readily infects the intestinal lining of C. elegans without significantly affecting its viability. Our observation suggests extending the use of the C. elegans model system for the study of host parasite relationships, to address problems concerning the biology of S. typhi.
 
Supported by UNESCO / MIRCEN network 
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